Living Skin Substitutes: Survival and Function of Fibroblasts Seeded in a Dermal Substitute in Experimental Wounds

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منابع مشابه

Viability and function of autologous and allogeneic fibroblasts seeded in dermal substitutes after implantation.

BACKGROUND Fibroblast-seeded collagen sponges have been used for the treatment of skin defects and skin ulcers. However, the viability of the fibroblasts after implantation is still unknown. The objective of this study was to investigate the viability and distribution of autologous and allogeneic fibroblasts after implantation and to clarify which type is more effective for wound healing. MAT...

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Microporous Dermal-Mimetic Electrospun Scaffolds Pre-Seeded with Fibroblasts Promote Tissue Regeneration in Full-Thickness Skin Wounds

Electrospun scaffolds serve as promising substrates for tissue repair due to their nanofibrous architecture and amenability to tailoring of chemical composition. In this study, the regenerative potential of a microporous electrospun scaffold pre-seeded with dermal fibroblasts was evaluated. Previously we reported that a 70% collagen I and 30% poly(Ɛ-caprolactone) electrospun scaffold (70:30 col...

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Correction: Microporous Dermal-Mimetic Electrospun Scaffolds Pre-Seeded with Fibroblasts Promote Tissue Regeneration in Full-Thickness Skin Wounds

open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Treatment of Leg Chronic Wounds with Dermal Substitutes and Thin Skin Grafts

Tissue repair is a natural process occurring any time the skin is injured. Repair is achieved through different successive phases: inflammation, formation of granulation tissue, forma‐ tion of the extracellular matrix (ECM), and remodeling. ECM plays an important role in tis‐ sue regeneration representing the principal component of the dermal skin layer. The composition of ECM includes proteogl...

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ژورنال

عنوان ژورنال: Journal of Investigative Dermatology

سال: 1998

ISSN: 0022-202X

DOI: 10.1046/j.1523-1747.1998.00459.x